Home › MCQs › MBBS › Question #10160
Back to Questions
MBBS QUESTION #10160
Question 1
Failure of neural tube closure at its caudal end typically results in which congenital anomaly?
  • Anencephaly
  • Spina bifida✔️
  • Holoprosencephaly
  • Cleft palate
Correct Answer Explanation
Failure of caudal neuropore closure produces spina bifida (a spectrum from occulta to myelomeningocele), while failure of the rostral neuropore produces anencephaly. Maternal folic acid supplementation reduces the risk of both.