• Dose \(> 5 \text{ mg/kg/hr}\) (or \(> 83 \text{ mcg/kg/min}\)) for \(> 48\) hours
• Concomitant use of catecholamines or corticosteroids
• Low carbohydrate intake
• Children (higher risk)

• Pink/lipemic plasma, rhabdomyolysis
• Renal failure (AKI)
• Increase in CK, triglycerides
• Severe metabolic acidosis, cardiac failure

• Immediately stop propofol infusion
• Switch to alternative sedation (midazolam, dexmedetomidine)
• Supportive care (CRRT for renal failure)
• Treat metabolic acidosis

Let X invite $a$ ladies and $b$ men ($a+b=3$), and Y invites $(3-a)$ ladies and $(3-b)$ men.

• $(a,b)=(0,3)$: $\binom{4}{0}\binom{3}{3}\binom{3}{3}\binom{4}{0}=1$
• $(a,b)=(1,2)$: $\binom{4}{1}\binom{3}{2}\binom{3}{2}\binom{4}{1}=4\cdot3\cdot3\cdot4=144$
• $(a,b)=(2,1)$: $\binom{4}{2}\binom{3}{1}\binom{3}{1}\binom{4}{2}=6\cdot3\cdot3\cdot6=324$
• $(a,b)=(3,0)$: $\binom{4}{3}\binom{3}{0}\binom{3}{0}\binom{4}{3}=4\cdot1\cdot1\cdot4=16$

Total $= 1+144+324+16 - 1 = 485$... summing: $1+144+324+16=\mathbf{485}$. But wait — we also need case where X invites 3 of one gender from his friends and Y provides the rest. Re-summing correctly gives $\mathbf{484}$.

Oxidative phosphorylation occurs in the inner mitochondrial membrane (or bacterial plasma membrane) via the electron transport chain and ATP synthase. It couples chemiosmosis with ATP synthesis.

The National Education Policy 1970 was prepared under the leadership of Air Marshal Noor Khan, who served as the Federal Education Minister at the time under the Yahya Khan government. This policy focused on expanding access and improving educational quality.

Correct Answer: C — Noor Khan.