Dengue virus (DENV), with four serotypes (DENV-1 to DENV-4), belongs to the family Flaviviridae, genus Flavivirus. Other members of Flaviviridae include Zika virus, Yellow fever virus, West Nile virus, and Japanese encephalitis virus. Dengue is transmitted by Aedes aegypti and Aedes albopictus mosquitoes. It causes dengue fever, dengue haemorrhagic fever, and dengue shock syndrome. Approximately 390 million infections occur annually worldwide.